About CTI Tracker
What Is CTI Tracker?
CTI Tracker is a database that contains information on contraceptive programs in development, such as products in early, pre-clinical and clinical stages of development as well as products with regulatory approval in only one country. The database also includes an archive of leads and products no longer in active development.
CTI Tracker is managed by FHI 360 as part of the Contraceptive Technology Innovation Exchange—or CTI Exchange—with support from the Gates Foundation.
What Is Included in CTI Tracker?
The CTI Tracker includes leads and products with potential, intended or confirmed contraceptive indications.
Contraceptive Lead: A chemical compound or biological molecule that shows promising biological activity for evolution into a contraceptive method. Leads are a starting point for further evaluation, modification and formulation to optimize their properties and potentially develop new drugs.
Contraceptive Product: A dosage form that contains one or more active pharmaceutical ingredients (APIs) believed to be associated with a contraceptive effect, a device intended to achieve contraceptive efficacy without an API, or a combination of the two. To be considered a “product,” it should be, at minimum, evaluated through studies under the scope of Good Laboratory Practice.
What Isn’t Included in CTI Tracker?
The Tracker does not include biological targets, leads or products for which no contraceptive indication has been evaluated or hypothesized, contraceptive products developed solely for veterinary use, or contraceptive products that have WHO prequalification or regulatory approval in more than one country.
How Is CTI Tracker Updated?
A pipeline database of contraceptive products has been developed and curated by the CTI Exchange since its inception. Starting in 2024, this database has gone through a rigorous annual review and updating process.
This update includes a substantial review of the scientific literature and cross-checks with the Male Contraceptive Initiative’s NHRMC database, the Multipurpose Prevention Technologies (MPT) Product Development Database, the NIH and Gates Foundation grantee databases, and clinicaltrials.gov. Updates are also informed by regular media monitoring for press releases and announcements within the scientific community.
This annual review is conducted in consultation with a panel of experts. Whenever possible, contraceptive researchers and developers themselves are contacted to provide details and updates to project/product information.
Contact Us
For more information about CTI Tracker, or if you would like to add an additional entry to the database, please email us at [email protected].
Additional Resources
For additional resources and updates from the world of contraceptive innovation, visit the CTI Exchange homepage, Events page, Opportunities page and Resource Collections. If you are looking for additional information related to the contraceptive development pipeline, try these resources:
- NIH’s Contraceptive Infertility Database (CITDBase) is a curation of public databases for the purpose of providing a list of human REPRODUCTIVE SYSTEM/TISSUE SPECIFIC contraceptive targets for investigators working in the field.
- MCI’s Non-hormonal, Reversible Male Contraception Database (NHRMC database) features over 100 different non-hormonal male birth control methods that have been identified to date.
- IMPT’s Multipurpose Prevention Technologies (MPT) Product Development Database (MPT Database) includes products that deliver varied combinations of HIV prevention, other STI prevention, and contraception and that are currently funded and in active development, spanning a range of delivery types and indications.
Disclaimer
The information provided on this website is for educational and research purposes. It is not intended as medical advice for patients learning about their contraceptive options, and it should not be used for purposes of medical diagnosis or treatment or as a substitute for medical advice from qualified medical professionals.
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