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Inactive
Last updated: May 29, 2025

Cinchonine Derivatives

3-(1-alkyl/aminoalkyl-3-vinyl-piperidin-4-yl)-1-(quinolin-4-yl)-propan-1-one, Quinine

  • User: Female
  • Hormonal: Non-Hormonal
  • Delivery type:
    • Vaginal Gel
  • Intended Duration:
    • Pericoital
  • Development Stage: Discovery & Early Development
  • Developer(s)/researcher(s): Central Drug Research Institute, Lucknow; University of Lagos
Details
  • API: Cinchonine Derivatives - Multiple
  • Mechanism of Action:
    • Inhibition of Sperm Motility
    • Ovulation Inhibition
  • Regimen: On Demand
  • MPT: Undetermined
Product Status

No Indication of Development after 2018

History

2012: Central Drug Research Institute Lucknow publishes early-stage results suggesting the potential use of Cinchonine Derivatives as spermicidal agents

2018: University of Lagos publishes separate research on Quinine's potential to suppress ovulation, studied in rats. 

Publications

doi: 10.1016/j.bmcl.2012.06.062

PMID: 30602950