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Inactive
Last updated: November 18, 2025

ENG + E2 Vaginal Ring

Merck Vaginal Ring, MK-8342B

  • User: Female
  • Hormonal: Hormonal
  • Delivery type:
    • Vaginal Ring
  • Intended Duration:
    • Undetermined
  • Development Stage: Phase III
  • Developer(s)/researcher(s): Merck
Details
  • API: Etonogestrel, Estradiol
  • Target: Estrogen Receptor, Progesterone Receptor, Androgen Receptor
  • Mechanism of Action:
    • Ovulation Inhibition
    • Cervical Mucus Changes
    • Endometrial Changes
  • Inactive Materials: Silicone
  • Regimen: Undetermined
  • MPT: Not Potential MPT
Product Status

Merck has terminated R&D for the method, including terminating active trials for a potential therapeutic indication

History

Phase III Clinical Trial for therapeutic indication was terminated prematurely. No subsequent public development information. 

Additional Information