Gossypol
- User: Male
- Hormonal: Non-Hormonal
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Delivery type:
- Oral
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Intended Duration:
- Permanent
- Short-Acting
- Development Stage: Phase I
Details
- API: Gossypol
- Target: Undetermined - Likely Dehydrogenase Enzymes
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Mechanism of Action:
- Reduced Sperm Production
- Inactive Materials: Undetermined
- Regimen: Undetermined - Likely 1 Pill/Day
- MPT: Not Potential MPT
Product Status
Concerning side effect profile and variable impact on fertility appear to have led to total discontinuation of research
History
See linked literature below for information on safety and biocompatibility
In 1986, WHO discontinued research on this drug due to concerns regarding toxicity and reversibility (~40% of clinical trial participants did not regain fertility). Research continued in Brazil and elsewhere at least through 2002.