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Inactive
Last updated: January 7, 2026

Copper + LDPE Nanocomposite IUD

Cu/LDPE/MVQ IUD

  • User: Female
  • Hormonal: Non-Hormonal
  • Delivery type:
    • Intrauterine
  • Intended Duration:
    • Long-Acting
  • Development Stage: Phase II
  • Developer(s)/researcher(s): Tongji Medical College at Huazhong University of Science and Technology Dayu Medical Devices
Details
  • API: Copper
  • Mechanism of Action:
    • Cervical Mucus Changes
    • Inhibition of Sperm Motility
    • Inhibition of Sperm Capacitation
  • Inactive Materials: Low-Density Polyethylene Methyl Vinyl Silicone Rubber
  • Regimen: 1 Insertion/5 Years
  • MPT: Not Potential MPT
  • Promising Attributes: Consistently found to be safe and effective. May offer an alternative to traditional copper IUDs.
Product Status

No evidence of development after 2019. Given substantial product interest from 2004-2019, record will be monitored for future development.

History

Evaluated through both clinical and non-clinical studies beginning in 2004. The product has had a number of different designs and composite formulations. As of 2025, development appears to be inactive. 

Publications

doi: 10.1016/j.contraception.2019.03.049
doi: 10.2147/IJN.S169114
doi: 10.1016/j.contraception.2018.06.002
doi: 10.1016/j.msec.2018.04.025
doi: 10.2147/IJN.S56756
doi: 10.1371/journal.pone.0074128
doi: 10.1016/j.colsurfb.2013.03.036
doi: 10.1016/j.msec.2013.03.012
doi: 10.1016/j.actbio.2011.09.024
doi: 10.1007/s10856-011-4347-y
doi: 10.1016/j.contraception.2010.07.015
doi: 10.1016/j.contraception.2008.07.018
doi: 10.1007/s11684-007-0078-3
doi: 10.1016/j.contraception.2007.06.006
doi: 10.1016/j.fertnstert.2006.11.122
doi: 10.1016/j.contraception.2006.09.012
doi: 10.1002/jbm.b.30548