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Last updated: January 13, 2026

Dapivirine + Copper + Zinc IVR MPT

  • User: Female
  • Hormonal: Non-Hormonal
  • Delivery type:
    • Vaginal Ring
  • Intended Duration:
    • Short-Acting
  • Development Stage: Discovery & Early Development
  • Developer(s)/researcher(s): Queen's University Belfast
Details
  • API: Dapivirine, Copper, Zinc
  • Mechanism of Action:
    • Anti-Microbial
    • Inhibition of Sperm Motility
    • Inhibition of Sperm Capacitation
  • Inactive Materials: Silicone
  • Regimen: Not Yet Determined
  • MPT: Potential MPT
  • Promising Attributes: The method would be user controlled and non-hormonal, both characteristics aligned with user interest, and would provide protection against both pregnancy and HIV.
Product Status

Active/Recent Early Development

History

2025: Queen's University Belfast publishes results of release profile analysis of IVRs integrating Dapivirine, copper, and zinc, concluding that these materials can be effectively integrated into a ring format and are compatible with one another.

Publications