Injectable Nanoparticles for Targeted Exogenous Testicular Hyperthermy
Magnetic Testicular Hyperthermy, Near-Infrared Testicular Hyperthermy, Metallic Nanoparticles
- User: Male
- Hormonal: Non-Hormonal
-
Delivery type:
- Testicular
-
Intended Duration:
- Short-Acting
- Development Stage: Pre-Clinical
- Developer(s)/researcher(s): Nantong University
Details
- API: Not Yet Determined
- Target: N/A
-
Mechanism of Action:
- Reduced Sperm Production
- Inhibition of Sperm Motility
- Inactive Materials: Human Heavy Chain Ferritin (HFn)
- Regimen: Not Yet Determined
- MPT: Not Potential MPT
- Promising Attributes: This has potential to be a noninvasive and simple method for male contraception.
Product Status
Active Pre-Clinical Research
History
Researchers have been exploring the utilization of human heavy chain ferritin (HFn) nanocarriers loaded with aggregation-induced emission luminogens (AIEgens) for noninvasive, controllable male contraception guided by Near-Infrared-II (NIR-II) fluorescence imaging. The HFn-caged AIEgens (HFn@BBT) are delivered via intravenous injection and activated by near-infrared irradiation. They published their most recent findings in 2024.