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Last updated: May 21, 2026

Trifunctional TNG Gel

Tri-Active Contraceptive Gel

  • User: Female
  • Hormonal: Non-Hormonal
  • Delivery type:
    • Vaginal Gel
  • Intended Duration:
    • Pericoital
  • Development Stage: Pre-Clinical
  • Developer(s)/researcher(s): Beijing Institute of Geriatrics, North Carolina State University
Details
  • API: Gossypol-Acetic Acid, Tenofovir, Nitroglycerin
  • Target: Lactate Dehydrogenase C4
  • Mechanism of Action:
    • Inhibition of Sperm Capacitation
    • Inhibition of Sperm Motility
    • Anti-Microbial
  • Inactive Materials: Carbomer
  • Regimen: On Demand
  • MPT: Potential MPT
  • Promising Attributes: Spermicidal gels may meet consistent user demand for user-controlled, non-hormonal pericoital methods. This gel is not only contraceptive but has the potential to prevent sexually transmitted diseases and increase sexual frequency and enhanced erection.
Product Status

Active Pre-Clinical Research

History

See publications listed below for information on safety and biocompatibility

Research conducted and published in 2021 including in vitro and rat testing to confirm contraceptive effects of the gel. Following this study a provisional patent was filed for this gel.

Publications

Additional Information