Acetic Acid Thermoreversible Gel
- User: Female
- Hormonal: Non-Hormonal
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Delivery type:
- Vaginal Gel
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Intended Duration:
- Pericoital
- Development Stage: Phase II
- Developer(s)/researcher(s): National Research Institute for Family Planning, China
Details
- API: Acetic Acid
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Mechanism of Action:
- Inhibition of Sperm Motility
- Inhibition of Sperm Capacitation
- Anti-Microbial
- Regimen: On Demand
- MPT: Potential MPT
- Promising Attributes: An on-demand MPT gel would provide user-controlled dual protection from pregnancy and STIs. Low-concentration acetic acid gels are commercially available for maintenance of vaginal pH, which may support regulatory approval.
Product Status
Active/Recent Clinical Development
History
2024: Developers initiate Phase II trial with 240 participants from four tertiary hospitals, intended to evaluate the safety and efficacy of an acetic acid-based vaginal gel in comparison to an approved spermicide.