Ulipristal Acetate Vaginal Ring + Oral LNG
- User: Female
- Hormonal: Hormonal
-
Delivery type:
- Vaginal Ring
- Oral
-
Intended Duration:
- Not Yet Determined
- Development Stage: Phase II
- Developer(s)/researcher(s): Population Council
Details
- API: Ulipristal Acetate, Levonorgestrel
-
Mechanism of Action:
- Endometrial Changes
- Cervical Mucus Changes
- Ovulation Inhibition
- Inactive Materials: Silicone
- MPT: Not Potential MPT
- Promising Attributes: The combination of UPA and LNG is theorized to contribute to superior bleeding management and multi-mechanism contraceptive effect
Product Status
No indication of development after 2017
History
Evaluated through a Phase I/II study (n=19) intended to document effect on ovulation, endometrium, and bleeding from 2500 microgram/day UA vaginal ring combined with an oral dose of either a single or repeat dose of 1.5mg oral LNG.