3D-Printed Lactic Acid + GML Intravaginal Ring
- User: Female
- Hormonal: Non-Hormonal
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Delivery type:
- Vaginal Ring
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Intended Duration:
- Short-Acting
- Development Stage: Discovery & Early Development
- Developer(s)/researcher(s): UNC Chapel Hill, North Carolina State University, CONRAD
Details
- API: Lactic Acid, Glycerol Monolaurate
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Mechanism of Action:
- Inhibition of Sperm Capacitation
- Inhibition of Sperm Motility
- Inactive Materials: SIL 30 Resin
- Regimen: Not Yet Determined
- MPT: Not Potential MPT
- Promising Attributes: Not Yet Established - Concept is in Early Development
Product Status
Active/Recent Early Development
History
2026: UNC Chapel Hill, NC State, and CONRAD at Old Dominion University publish results of formulation/drug loading, drug release, and physiochemical interaction evaluation for a 3D-printed IVR loaded with two non-hormonal contraceptive agents, lactic acid and glycerol monolaurate. Results suggest that co-delivery of the two APIs for 30+ days is viable and the device is likely to be biocompatible and stable. They indicate their intention to proceed to a sheep model for in vivo testing.