Doughnut Microspheres with PMCA Inhibitors
Plasma Membrane Calcium ATPase (PMCA) Inhibitors
- User: Female
- Hormonal: Non-Hormonal
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Delivery type:
- Multiple
- Vaginal Gel
- Vaginal - Other
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Intended Duration:
- Short-Acting
- Development Stage: Discovery & Early Development
- Developer(s)/researcher(s): University of Manchester, Max Planck Institute
Details
- API: Undetermined
- Target: PMCA4
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Mechanism of Action:
- Inhibition of Sperm Motility
- Inhibition of Sperm Capacitation
- Inactive Materials: Undetermined
- Regimen: Undetermined
- MPT: Not Potential MPT
Product Status
No evidence of publication focused on specific compounds or delivery methods. Final publication released in 2010.
History
2010: Plasma membrane calcium/calmodulin-dependent ATPase isoform 4 identified as a potential contraceptive target. Researchers propose a delivery system of microspheres loaded with PMCA inhibiting compounds.