Carica Papaya Extract
- User: Female/Male
- Hormonal: Not Yet Determined
-
Delivery type:
- Not Yet Determined
-
Intended Duration:
- Not Yet Determined
- Development Stage: Pre-Clinical
- Developer(s)/researcher(s): University of Rajasthan, India, Punjab Agricultural University and Thapar Institute
Details
- API: Chloroform Extract of Carica Papaya Seed
- Target: Not Yet Determined
-
Mechanism of Action:
- Reduced Sperm Production
- Inhibition of Sperm Motility
- Inhibition of Sperm Capacitation
- Inactive Materials: Not Yet Determined
- Regimen: Not Yet Determined
- MPT: Not Potential MPT
- Promising Attributes: To be established - concept is in early development
Product Status
Most recent study suggests non-viability as modern contraceptive method. Record will be reviewed in 2025 for additional development.
History
See linked literature below for information on safety and biocompatibility
The contraceptive potential, as both a male and female method, of Carica Papaya seed extract has been evaluated through in vivo research since at least 1995.
2024: Rat study conducted by the Punjab Agricultural University and Thapar Institute found that while solid lipid nanoparticles loaded with papaya seed chloroform extract did impact sperm motility, viability, count, and other fertility markers in male rats, reproductive success rates were still 16-67%.