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Last updated: April 9, 2025

GSK3α-Inhibiting Compound

BRD0705

  • User: Male
  • Hormonal: Non-Hormonal
  • Delivery type:
    • Not Yet Determined
  • Intended Duration:
    • Not Yet Determined
  • Development Stage: Discovery & Early Development
  • Developer(s)/researcher(s): Kent State University, Broad Institute, Manipal Centre for Biotherapeutics Research
Details
  • API: BRD0705
  • Target: GSK3α
  • Mechanism of Action:
    • Inhibition of Sperm Capacitation
    • Inhibition of Sperm Motility
  • Inactive Materials: Not Yet Determined
  • Regimen: Not Yet Determined
  • MPT: Not Potential MPT
  • Promising Attributes: To be established - concept is in early development
Product Status

Active Early Development 

History

2025: Developers publish results of early development animal studies, which suggest reliable impairment of sperm maturation and return to fertility following the conclusion of treatment

Publications