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Active
Last updated: November 12, 2025

Nestorone-Only Vaginal Ring

  • User: Female
  • Hormonal: Hormonal
  • Delivery type:
    • Vaginal Ring
  • Intended Duration:
    • Short-Acting
  • Development Stage: Pre-Clinical
  • Developer(s)/researcher(s): Population Council
Details
  • API: Nestorone
  • Target: Progesterone Receptor
  • Mechanism of Action:
    • Cervical Mucus Changes
  • Regimen: Not Yet Determined
  • MPT: Not Potential MPT
  • Promising Attributes: Developer indicates "users of the Nestorone-only intravaginal ring are expected to have an improved-side effect profile...and a rapid return to fertility"
Product Status

Active Pre-Clinical Evaluation

History

2025: Developers announce active development and intent to file for an IND and initiate Phase II clinical evaluation

Additional Information