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Last updated: January 13, 2026

Drospirenone-Only Emergency Contraceptive Pill

  • User: Female
  • Hormonal: Hormonal
  • Delivery type:
    • Oral
  • Intended Duration:
    • Emergency
  • Development Stage: Phase II
  • Developer(s)/researcher(s): University of Colorado, Denver
Details
  • API: Drospirenone
  • Target: Progesterone Receptor
  • Mechanism of Action:
    • Ovulation Delay
  • Regimen: On Demand
  • MPT: Not Potential MPT
  • Promising Attributes: Drospirenone has the potential for less-restricted efficacy in overweight and obese users than other existing oral EC methods.
Product Status

While a Ph II trial was registered on Clinicaltrials.gov, there is no indication that the study initiated. Record will be monitored and moved to inactive when appropriate.

History

2022: The Society of Family Planning awards researchers at the University of Colorado Denver a small grant to support clinical research on the potential use of a drospirenone-only pill as emergency contraceptive. 
2022: Researchers indicate intent to enroll 35 participants in dose-range finding study on the novel EC method, with planned study initiation in 2023.

Additional Information