Researchers Create Lab Model That Could Lead to New Non-Hormonal Methods

Man in a whote coat and blue scrups stands in a laboratory OHSU/Christine Torres Hicks
News POSTED Jan 15, 2025 By CTI Exchange Staff

Researchers at Oregon Health & Science University (OHSU) have developed a lab model to study how changes in cervical mucus during the menstrual cycle regulate fertility. This breakthrough could pave the way for new, non-hormonal birth control methods. 

The study, led by Dr. Leo Han and published in the journal Biology of Reproduction, analyzed genetic activity in lab-cultured cervical cells. The team identified hundreds of genes that could be targeted to block sperm, offering a potential alternative for those who cannot or prefer not to use hormonal contraceptives. 

Dr. Katrina Rapp, the lead author, emphasized the importance of this research in addressing unmet contraceptive needs. The cervical mucus naturally regulates fertility, making it an ideal target for non-invasive contraceptive methods.