Emergency Oral Meloxicam
- User: Female
- Hormonal: Non-Hormonal
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Delivery type:
- Oral
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Intended Duration:
- Emergency
- Development Stage: Phase I
- Developer(s)/researcher(s): CONRAD, ICMER
Details
- API: Meloxicam
- Target: Cyclooxygenase
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Mechanism of Action:
- Ovulation Delay
- Inactive Materials: Undetermined
- Regimen: Taken after Unprotected Intercourse for 5 Days
- MPT: Not Potential MPT
Product Status
No indication of active development after 2013.
History
Non-human primate evaluation conducted 2010-2013 suggested immediate administration of oral meloxicam for 5 days following intercourse could consistently disrupt ovulation and prevent pregnancy. 2010 clinical evaluation in 27 surgically sterilized human volunteers found that a 30mg dose/day for 5 days in the late follicular phase produced ovulatory dysfunction in 90.9% of participants with no serious adverse events.